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The weekend sees the initial Wear-Tyne derby after 2024, but which side will celebrate – the Black Cats or the Magpies?
"For most of last season, it was unthinkable the Wearside club earning promotion and challenging with Eddie Howe's Newcastle, let alone being above them in the table," remarked football expert Chris Sutton.
"Things are very different now, and the way they play leads me to believe they've got a real chance."
Sutton is making scoreline guesses for all 380 Premier League games this season, against artificial intelligence, readers and a range of guests.
For this weekend's fixtures, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the national gaming squad – the Football Association's formal esports team – at the gaming title Uefa eEuro 2025 finals tournament, which is being held at Twickenham Stadium on Saturday.
Viewers can catch Uefa's YouTube, Instagram Live and short-form video channels, as well as EA Sports FC Twitch and its YouTube counterpart and England's Twitch.
Do you agree with their forecasts? You can make your own predictions below.
The most commonly selected scoreline chosen for each game is featured in the tables at the end of this page.
Predicting the right outcome (picking a win, draw or defeat) is worth 10 points. An accurate scoreline earns 40 points.
Ray, who also plays his club side and the Premier League champions as well as England, is making his debut at the eEuros finals after successfully navigating the preliminary stage.
Eight players will fly the flag at the finals in a single-elimination, vying for a $100,000 prize pool and a coveted spot in the global championship qualifiers, with Denmark's Anders Vejrgang looking to retain the title he won last year.
"My mindset is really good for it," Ray remarked. "I have a really good coach alongside me and training has been going well.
"It is invariably an honour to play for your country. Of course when you are younger, you fantasise about doing it as an actual footballer, but when you pursue a career in this profession and there is an opportunity to represent England, wearing the Three Lions is something special.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him throughout the year just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"I believe he is the best player in the world so defeating him in a tournament like this just delivers a huge surge of confidence."
Premier League Predictions
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The Blues were excellent against Arsenal at the end of November, when they secured a point after being reduced to 10 men, and many thought they've turned a corner, they could possibly be title contenders.
In the matches following, however, they were outfought by Leeds, looked uninspired against Bournemouth and this week got turned over by Atalanta in the Champions League.
So boss Enzo Maresca desperately requires a win here to restore momentum, but it will be a challenge because the Merseyside club are such a potent team.
Two of their stars are playing at the top of their game and they have got a bit of form at the moment.
On form you would likely back Everton, while the most prudent prediction would likely be a draw, but I'm going against logic.
They have not given me any compelling evidence to back them recently, but I just have a gut instinct they will emerge victorious because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be intriguing to see what we get from the Reds.
It was great to see for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday after all the discussion with Mohamed Salah this week.
Slot should not have to put up with that distraction. I know Salah has been a icon for Liverpool but fundamentally Slot just wants to win games and there is no ulterior motive in his team selection.
They changed their shape against Inter and went with a midfield diamond and two up top.
The media is going to be talking about whether Salah is included for this game, but the only way he is going to be reintegrated is if he makes amends.
Slot's attention will be on winning this game, but it is a challenging encounter.
It's fair to say it is the same for most teams but I find Brighton so hard to predict. I always feel they have got a goal in them, but they are vulnerable at the back too.
The Merseysiders need to get back to winning consistently, but I am not sure how much their efforts at the San Siro will have affected their stamina.
I have whacked a couple of Brighton players in my FPL team, so they will probably lose now - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the week off while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to be pegged back late on.
Aside from their superb performance against Everton a couple of weeks ago, Newcastle's away form has been poor, especially straight after they've played in the Champions League.
The pattern suggests that trend to continue on Sunday, and their fatigue is likely to be a key element in how this game goes because of Sunderland's intensity.
It was evident how relentless Regis le Bris's side are. They bullied the Gunners, and it was incredible to watch.
Many pundits talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been excellent, but Noah Sadiki, who plays alongside him, has also been one of the top transfers and warrants praise too.
I am expecting this being the best game|most exciting fixture
